Does Orange Juice Have a Role in Cancer Recovery?

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woman eating orangeIn a forthcoming review article from Nutrition and Cancer: An International Journal, a publication of Routledge, researchers review available evidence that links orange juice with cancer chemoprevention. The review article, “Orange Juice and Cancer Chemoprevention” discusses the putative mechanisms involved in the process, the potential toxicity of orange juice, and the available data in terms of evidence-based medicine.

Orange juice has many potential positive effects when it comes to cancer, particularly because it is high in antioxidants from flavonoids such as hesperitin and naringinin. Evidence from previous in vitro studies has indicated that orange juice can reduce the risk of leukemia in children, as well as aid in chemoprevention against mammary, hepatic, and colon cancers. Biological effects of orange juice in vitro are largely influenced by the juice’s composition, which is dependent on physiological conditions of the oranges such as climate, soil, fruit maturation, and storage methods post-harvest.

The researchers acknowledge potential toxicity from orange juice if consumed in excess amounts—especially for children, hypertensive, kidney-compromised, and diabetics. Excessive drinking of orange juice for individuals from these groups has the potential to create noxious effects, hyperkalemia, and has been associated with both food allergies and bacterial outbreaks in cases where the juice was unpasteurized. “Excessive intake of any food, even for the healthiest, can lead to oxidative status imbalance,” wrote the researchers.

Further research is highly recommended to determine the biological connection between orange juice and cancer chemoprevention. Issues such as the type of cultivar and the amount consumed will also need clarification.

Overall, the review article summarizes several biological effects of orange juice that can contribute to chemoprevention, including antioxidant, antimutagenic and antigenotoxic, cytoprotective, hormonal, and cell signaling modulating effects. Orange juice has antimicrobial and antiviral action and modulates the absorption of xenobiotics. “OJ could contribute to chemoprevention at every stage of cancer initiation and progression,” the researchers explained. “Among the most relevant biological effects of OJ is the juice’s antigenotoxic and antimutagenic potential, which was shown in cells in culture and in rodents and humans.”

My recommendation:  One (1) glass a day.  Drink OJ that is fortified with vitamin D.


Breaking News: Important NY Times Blog

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The over-diagnosis and over-treatment of cancer is an issue the Cancer Recovery Foundation Group of Charities has long raised.  In today’s NY Times well.blogs, Scientists Seek to Rein In Diagnoses of Cancer, the subject is finally receiving national attention.  I ask every cancer patient to carefully study this article.  The implications are sad and astounding.  If you have recently been given a breast or prostate cancer diagnosis, challenge it.  Ask.  Ask.  Ask.  Questioning the diagnosis and treatment is your point of greatest power.

Kerry Questioning Chemo

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Hi Greg,

Many thanks for sharing your story and for being available to help others. I have ampullary cancer with liver and possible lung metastasis. Oncologists seem certain that I’m a goner, and recommend chemotherapy to keep me alive a bit longer. They have very little experience with this type of cancer, and say they generally treat it the way they would treat pancreatic cancer. I totally disagree with their prognoses, realizing that a certain, albeit small, percentage of people in my condition survive for the long term. I’m determined to be one of them, and I don’t think it will happen by accident. I will have to make it happen. Outwardly, my health is excellent. Vital signs are consistently normal, my color is good, my weight is holding steady and I’m doing a lot of walking and some weight lifting. My life partner/caregiver is totally wonderful and with me every step of the way; and my family is very supportive. I’m extremely grateful for all of these. I’ve had two months of chemotherapy with Gemzar and Cisplatin, which I tolerated very well. The most recent scan shows that the tumors grew slightly, and the oncologist said this could have happened between the time of the previous scan and the beginning of the chemotherapy, and wants to do six more weeks with Gemzar and Cisplatin. Meanwhile, I went to another treatment center, and while their approach was considerably better than others, the treatment plan was about the same. The only difference was that the CTCA oncologist said the scans make it clear enough that the current regimen is not working, and recommended going on to a more aggressive chemotherapy (Xeloda). He seemed slightly more optimistic about my long-term survival possibilities, but was not inspiring. I have strong misgivings about taking any more chemotherapy, given that several sources tell me it’s effective against only a handful of cancers, and mine isn’t one of them. Also, the oncologists prescribing it are not planning on my long-term survival, and chemotherapy attacks my health and immune system at a time when I might very well need them most. I also have strong misgivings about quitting chemotherapy, because it just might be attacking tumors that aren’t visible, and conventional medicine doesn’t seem to offer much else. Is this the time to quit chemotherapy, continue the previous regimen, or start a more aggressive regimen? Any guidance or encouragement would be greatly appreciated.




I cannot give you medical advice.  But I can tell you that the use of chemotherapy is third in effectiveness to surgery and radiation. 

Make sure you are in touch with the ampullary cancer survivors at

If you have read some of my books, you know that I am not a fan of chemo.  The facts do not support its widespread use.

Kerry, my guidance is this:  if you have not had the surgery, do so.  Think next of radiation seeds (brachytherapy).  And then chemo, perhaps fractionated doses in an attempt to stabilize the disease.   

Add to that a full holistic wellness program.  See below as a great starting point.  Build up your immune system.

You have the perfect attitude.  Survivors are fighters.  And you are certainly a warrior.

Stay in touch.  I wish you well.

pdf icon   Cancer Recovery Contract          pdf icon   Grocery List

Did you hear me scream just a moment ago?

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The National Cancer Institute just released a survival study comparing breast cancer patients who go on to consume high-fat dairy foods versus those who don’t.  What do you suppose the result was?  Not surprising—consuming high-fat dairy increases one’s chances of dying years earlier.

Why do we waste cancer research dollars “proving” something that is well-documented.  I first started writing about this in 1988.  We had the “proof” then.

Please know this—high-fat diets are correlated with both higher incidence and higher death rates from breast and ovarian cancer.  No fat/low fat—that’s the answer.  When in doubt, eat a plant!

Healthcare – CNN Broadcasts Award-Winning Documentary

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CNN will broadcast the award-winning documentary, “Escape Fire: The Fight to Rescue American Healthcare,” on Sunday, March 10 at 8:00pm and again at 11:00pm Eastern.

The film reveals flaws in the notion that the healthcare delivered via America’s patchwork of facilities, practitioners, and insurers offers good value for its outcomes.  Through the real-life experiences of physicians and patients, Escape Fire shows the tremendous pressures providers feel to reduce costs and limit patient interaction time – and the frustrations of patients struggling with preventable conditions that are often created or exacerbated by over-diagnosis, over-treatment and insufficient or inappropriate care.

It’s a story all cancer patients and family members need to understand.  Please share this message with those you love.  I hope you will watch.

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